A pragmatic trial is a type of clinical trial that aims to evaluate the effectiveness of an intervention in real-world clinical settings. These trials often involve a diverse population of participants and are designed to provide evidence on the impact of an intervention on outcomes that are relevant to clinical practice. Pragmatic trials are typically conducted with minimal additional resources or requirements beyond routine clinical care, making them more applicable to real-world settings and allowing for results that can be directly applied to everyday clinical decision-making.